Officials say a woman was driving from an on-ramp onto the US 60 when she hit a metering light post and spun to the HOV lane. A white truck driving in the lane rear-ended her and rolled over.
Debris from the original crash hit two other cars.
Police are investigating whether or not the woman was impaired during the crash.
The roadway was closed for several hours. Back-up on the US 60 appeared to go for miles.
The lanes of US 60 eastbound weren't affected.