It happened Thursday afternoon near Priest and Baseline, close to Arizona Mills Mall.
Police say the victim was walking to work when a man attacked her and raped her in public behind some bushes.
Police say the suspect is a black male, 22-25 years-old, 6'0" tall, shoulder length braided hair, with a medium build.
He was last seen wearing tan cargo shorts and a black short sleeve t-shirt.
The suspect left on foot from the scene of the crime, and Tempe Police are asking for anyone with information is asked to call Tempe Police at 480-350-8311.