It happened at the intersection of Scottsdale Road and McKellips. The area, which was shut down overnight, is back open on Saturday.
The shooting happened around 8 p.m. near the Food City parking lot. Police say there were two men inside a car when gunfire broke out inside the vehicle. The driver was shot in the head and died from a gunshot wound. After the shooting, the car rear-ended a second vehicle.
Police say the passenger in the car with the victim was extremely upset and has not been cooperating with the investigation.
Police are now trying to determine who fired the gun inside that car. Officers closed the area as they begin the investigation, and it re-opened on Saturday morning.