Dwyer previously pleaded not guilty to felony aggravated assault and eight misdemeanors charges. However, the case went back to a grand jury for reconsideration after a judge ruled that the prosecution didn't accurately describe several matters related to the victim's injuries.
Dwyer then was indicted again on the same charges. He's scheduled to be arraigned Monday in Maricopa County Superior Court in Phoenix.
Investigators say Dwyer broke his wife's nose during a July 21 argument, and the next day punched her.
After Dwyer's arrest in September, the Cardinals placed him on the reserve/non-football illness list. That meant he couldn't play for Arizona again during the 2014 season.