Nancy Guthrie: Florida lab encounters 'challenges' with mixed DNA found at home, sheriff says
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Pima County Sheriff Chris Nanos said there has been a snag at the private lab in Florida, testing mixed DNA samples found at Nancy Guthrie's home. He also told NBC News that his department has no names they're investigating related to the 84-year-old's disappearance. 

3-year-old girl abducted in Avondale, may be with 30-year-old woman
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Police are searching for 3-year-old Kehlani Rogers, who was last seen at her Avondale home late Friday night. FOX 10's Megan Spector has the latest on the abduction and the woman who she is believed to be with. 

Nancy Guthrie latest, global tariff updates & Iran | FOX 10 Talks
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Anchor Brian Webb & Executive Producer Trenton Hooker talk about the biggest news stories of the day. Reporter Megan Spector joins us to talk about an Amber Alert of a missing 3-year-old girl out of Avondale. Plus, we have the latest with Nancy Guthrie. Alex Vatanka, a Senior Fellow at the Middle East Institute, joins us to talk about the situation between the United States and Iran. Christine Abely, Assistant Professor of Law at the University of New Hampshire Franklin Pierce School of Law, joins to talk about tariffs.

idea Museum opens 3 new exhibits
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We're checking out the idea Museum's latest exhibits, including a Alanna Airitam's photography, a Rube Goldberg machine and "Artfully Absurd" near Robson and 1st St. in Mesa.

Spring Training with the Peoria Sports Complex grounds crew
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Spring Training is in full swing and Richard Saenz sees how his skills on the ball field measure up when he joins the Peoria Sports Complex grounds crew.

Nancy Guthrie: Day 21 search updates
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Feb. 21  marks day 21 since Nancy Guthrie, the 84-year-old mother of NBC "Today" show host Savannah Guthrie, disappeared from her Tucson-area home. Investigators believe she was taken against her will.

Taste of the Town: Presidio Cocina Mexicana
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Serving Michoacán-inspired Mexican homestyle cooking, Presidio Cocina Mexicana now has two locations in Phoenix.

Suspect awaiting extradition to Arizona
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Police say a suspect accused of killing a man at an Ahwatukee apartment complex near 44th St. and Chandler Blvd. was found in Massachusetts.

Weekend weather forecast - 2/21/26
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Highs are expected in the 70s for the Valley today, but the 90s are set to make a comeback soon.

Michael Bayne found dead in Mesa
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Michael Bayne's disappearance triggered an intensive search by detectives and a massive outpouring of support from the community.

AZ prison dept. to appeal health care ruling
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The Arizona Department of Corrections, Rehabilitation & Reentry said the agency will "aggressively appeal" a court ruling that ordered a takeover of the prison's health care system.

Trump tariff: SCOTUS rules they are illegal
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The U.S. Supreme Court has ruled that President Donald Trump's sweeping tariffs are illegal, but the White House is pushing. Meanwhile, some Arizona businesses are breathing a sigh of relief. FOX 10's Megan Spector has more.

Suns and D-backs | FOX 10 Talks Sports: Pregame
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The All Star break is over, and the Phoenix Suns have their eyes on a playoff run. Plus what are realistic expectations for the Arizona Diamondbacks this season? FOX 10 Sports Reporters Blake Niemann and Robby Baker break it all down.

Trump tariff: Arizona reacts to SCOTUS ruling
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On Feb. 20, the U.S. Supreme Court ruled that President Donald Trump's tariffs are illegal in a 6-3 ruling that states the President needed a distinct law from Congress for the tariffs. FOX 10's Megan Spector has more on local reaction to the ruling.

Peoria restaurant owner released from ICE custody
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A longtime West Valley restaurant owner who had been detained by ICE since May 2025 has been released from custody. The case has drawn national attention, with community members and lawmakers trying to help. FOX 10's Ellen McNamara reports.

Artemis II: NASA eyes March 6 moon mission launch
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NASA is one step closer to launching astronauts around the moon for the first time in over half a century, as the agency eyes a March 6 launch date for the Artemis II mission. Reporter Chelsea Torres has more, from Houston.

Road rage shooting: Ariz. family remembers victim
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There has been a string of road rage shootings and killings over the past several months in Maricopa County, and the family of one victim, along with prosecutors, are urging de-escalation. FOX 10's Megan Spector reports.

Nancy Guthrie: Tips continue to pour in for case
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As the search for Nancy Guthrie continues, investigators are also sifting through some 20,000 tips that have poured in, and one official said people should think before they call in with tips. FOX 10's Brian Webb reports.

Reese's: Family of original maker levels criticism
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A battle is brewing between the family behind Reese's and Hershey's, as a relative of the original maker of Reese's called out Hershey's for using cheaper ingredients and duping customers. Reporter Teresa Priolo has more.