The Arizona Department of Public Safety said the crash happened in the southbound lanes when a car hit the median, rolled over and landed on its roof.
The crash blocked multiple lanes along the freeway and caused heavy traffic backup.
The victim was hospitalized with serious injuries.
It's unknown what caused the driver to crash into the median.
Overturned car on Loop 101 and Cactus Road in Scottsdale on Dec. 21
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